The ability of microfluidic (MF) device technologies to provide a lot of information with a small amount of sample, the opportunities it provides increases their use in the medical field in the bedside monitoring in drug delivery systems.
In our project, it is aimed to design microfluidic pumps (MFP) to be used in medical field and conduct its production with 3D printer technologies First of all, MFP parts were designed and printed with the help of 3D printer and on AutoCAD. The poly(dimethylsiloxane) (PDMS) membrane that will enable MFP activation is produced in different thicknesses.Liquid PDMS was applied to the inner surfaces of MFP’s air and flow channel, PDMS membrane was placed between them and the parts were assembled in the oven. MFP has been connected to the pneumatic valve system, where operation codes have been prepared with Arduino Uno, and flow properties have been examined. The flow rate of MFP is ~ 50 µL/min at a maximum of 15 Hz and the backpressure is ~ 0.085 Pa under a maximum pressure of 3 bar.
As a result, MFP which is biocompatible, drug adaptable, portable, wearable technology applications potential and has suitable flow characteristics as a pharmaceutical pump has been developed. MFP introduced a microfluidic pump system which can make life easier for the patient and contribute to the national economy through domestic production and can be used as a drug pump in the treatment of diseases such as diabetes and cancer.